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Online Medical Symptom Checker  Symptoms & Signs Index
   Jaundice
 
Definition:
A yellowish pigmentation of the skin, tissues, and certain body fluids caused by the deposition of bile pigments that follows interference with normal production and discharge of bile (e.g. Hepatitis) or excessive breakdown of red blood cells (e.g. Hemolytic anemia, sickle-cell anemia).
 
Medical terms related to jaundice :
Icterus, Yellow Staining of Skin and Eyes, Icter, Yellow skin
 
Common causes of jaundice: 
o Alcohol Abuse and Alcoholism
o Breastfeeding jaundice (in infants, usually in first week of life)
o Breast milk jaundice (in infants):
Jundice that may occur during the second or third week of infants' life
o Newborn jaundice (physiologic jaundice)
o Gallstones
o
Viral hepatitis:
Hepatitis A, Hepatitis B, hepatitis C, hepatitis D, and hepatitis E
o Human Immunodeficiency Virus
o Pancreatitis
o
Drug-induced hepatitis:
Erythromycin sulfa drugs, antidepressants, anti-cancer drugs, Aldomet, rifampin, steroids, chlorpropamide, tolbutamide, oral contraceptives, testosterone, Isoniazide, propylthiouracil.
o
Hemolytic Anemia:
Anemia caused by excessive destruction of red blood cells because of chemicals, infections, or autoimmune diseases, e.g. Spherocytosis, Sickle Cell Anemia, Glucose-6-Phosphate Dehydrogenase Deficiency.

Other Causes of jaundice:
o Primary Biliary Cirrhosis
o Primary Sclerosing Cholangitis (PSC)
o Liver Cancer
o Pancreatic Cancer
o Autoimmune Hepatitis
o Biliary atresia
o Gallbladder Cancer
o malaria
o
Cirrhosis Of The Liver:
Fibrosis of the liver and the formation of regenerative nodules that is usually caused by chronic progressive damages to the liver,e.g. by alcohol abuse or hepatitis.
o
Gilbert Syndrome:
An inherited metabolic disorder characterized by elevated levels of mostly unconjugated serum bilirubin caused especially by defective uptake of bilirubin by the liver.
o Kernicterus:
Deposition of bile pigments in the nuclei of the brain and spinal cord causing degeneration of nerve cells.Kernicterus occurs usually in infants.
o
Sickle Cell Anemia:
A chronic anemia that occurs mostly in individuals with African or Mediterranean origin.

 

Call your doctor if jaundice is accompanied by: 
o Weight loss
o Fever, anorexia, urine color change
o white stool
o Starting a new drug
o Fasting
o Age over 55, depression, weight loss, mass on right upper abdomen

 
Diagnostic tests that may be performed include: 
o blood serum bilirubin
o liver function tests and cholesterol
o prothrombin time (PT)
o complete blood count (CBC)
o ultrasound of the abdomen
o liver biopsy
o urine and fecal urobilinogen
   
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Diagnosis of jaundice, Reasons of jaundice, Prevention of jaundice, Definition of jaundice, Treatments for jaundice


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